In 1948 a corticosteroid compound was administered for the first time to a patient affected by rheumatoid arthritis by Philip Showalter Hench, a rheumatologist at the Mayo Clinic in Rochester, Minnesota (USA).He was investigating since 1929 the role of adrenal gland-derived substances in rheumatoid arthritis.For the discovery of cortisone and its a

In reverse fault fracture zone of Tunbao Coal Mine, the coal pillar side roadway is affected by mining, which leads to large roadway deformation, roadway floor heave, coal pillar side wall heave, and local subsidence of Rhinestone roadway roof.Anchor stress was monitored by anchor dynamometer, and roadway stress distribution and roadway deformation

Beet cyst nematode (Heterodera schachtii Schmidt).Spreads extensively in different regions of sugar beet cultivation, and therefore many efforts are accomplished Router to prevent decrease of sugar and root yield caused by the disease.The most appropriate control method of this disease is improvement of resistant varieties.Wild species of procumben

BACKGROUND:Obstructive sleep apnea (OSA) is a well-established risk factor for hypertension and cardiovascular morbidity and mortality.More recently, OSA has been implicated as an independent risk factor for chronic kidney disease.Urinary neutrophil gelatinase-associated lipocalin (NGAL) is a well-accepted early biomarker of subclinical kidney tubu

HIV infection is controlled but not eradicated by combination antiretroviral therapy (cART), and persistence during therapy represents a substantial barrier to strategies to eradicate infection.The nature of persistence is uncertain, and a number of mechanisms have been proposed to explain HIV persistence in vivo, including low-level HIV replicatio